Abstract
With a growing global population, agricultural scientists are focusing on crop production management and the creation of new strategies for a higher agricultural output. However, the growth of undesirable plants besides the primary crop poses a significant challenge in agriculture, necessitating the massive application of herbicides to eradicate this problem. Several synthetic herbicides are widely utilized, with glyphosate emerging as a potential molecule for solving this emerging issue; however, it has several environmental and health consequences. Several weed species have evolved resistance to this herbicide, therefore lowering agricultural yield. The persistence of glyphosate residue in the environment, such as in water and soil systems, is due to the misuse of glyphosate in agricultural regions, which causes its percolation into groundwater via the vertical soil profile. As a result, it endangers many nontarget organisms existing in the natural environment, which comprises both soil and water. The current Review aims to provide a systemic analysis of glyphosate, its various effects on the environment, its subsequent impact on human health and animals, which will lead us toward a better understanding of the issues about herbicide usage and aid in managing it wisely, as in the near the future glyphosate market is aiming for a positive forecast until 2035.