Abstract
Calcium oscillations are rhythmic fluctuations of the intracellular concentration of calcium ions (Ca(2+)). As Ca(2+) evokes various cellular processes, its intracellular concentration is tightly regulated. Ca(2+) oscillations control biological events, including neuronal differentiation and proliferation of mesenchymal stem cells. The frequency and pattern of Ca(2+) oscillations depend on cell type. Researchers have studied Ca(2+) oscillations to better understand how cells communicate and regulate physiological processes. Dysregulation of Ca(2+) oscillations causes health problems, such as neurodegenerative disorders. This review discusses the potential functions of Ca(2+) oscillations in stem cells.