Abstract
Disclosure: J. Bello: None. E. Erhus: None. A. Caputi: None. S. Qaddorah: None. G.Y. Amdetsion: None. A. Ilelaboye: None. Trends in Heart failure hospitalization in patients with Type 1 DiabetesIntroduction: Patients with both type 1 and type 2 DM are at an increased risk for heart failure. Despite this, heart failure outcomes remains less well studied in type 1 DM. The objective of this study is to conduct an observational analysis of trends in heart failure hospitalizations among patients with T1DM, thereby raising awareness about the risk of heart failure and potential contributing factors within this vulnerable population. Methodology: This was a retrospective longitudinal study using data from the National Inpatient Sample from 2016 to 2021. Patients hospitalized with a primary diagnosis of heart failure and a secondary diagnosis of type 1 DM were identified using ICD 9 and 10 codes. Trends in outcomes were assessed, stratified by sociodemographic variables. The Primary outcome was mortality. Secondary outcomes were the length of hospital stay (LOS) and total hospital charge. Results and Discussion:The number of heart failure hospitalizations among patients with type 1 DM progressively increased from 7,734 in 2016 to 10,034 in 2021. Interestingly, this increase was mostly in young and middle-aged patients (P=0.01). The mean age at hospitalization down trended from 58.9 years to 57.7 years (P= 0.018). Mortality rates declined from 2.46% to a nadir of 1.84% in 2019 but then saw and upward trend to 2.15% in 2021. Caucasians consistently exhibiting higher rates (2.95%) compared to Black (1.4%) and Hispanic (2.58%) populations.The average LOS across the study period was 5.98 days (95% CI: 5.87-6.09), with a steady increase from 5.8 to 6.2 days. The total hospital charge also progressively increased after adjusting for inflation.The increased heart failure hospitalization in young and middle-aged patients with type 1 DM calls for more aggressive control of cardiovascular risk and screening for cardiovascular comorbidities in this population. Caucasians with type 1 DM and heart failure continued to exhibit relatively high mortality rate and special care is needed in the management of this population. Presentation: Saturday, July 12, 2025