BNT162b2 Messenger RNA Vaccination Did Not Prevent an Outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 Variant 501Y.V2 in an Elderly Nursing Home but Reduced Transmission and Disease Severity

BNT162b2信使RNA疫苗接种未能阻止养老院中严重急性呼吸综合征冠状病毒2型501Y.V2变种的爆发，但降低了传播和疾病严重程度。

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作者：Bailly,Benoit,Guilpain,Luc,Bouiller,Kevin,Chirouze,Catherine,N'Debi,Melissa,Soulier,Alexandre,Demontant,Vanessa,Pawlotsky,Jean-Michel,Rodriguez,Christophe,Fourati,Slim
期刊：Clinical Infectious Diseases影响因子：7.300
时间：2022起止号：2022 Feb 11;74(3):517-520
doi：10.1093/cid/ciab446

Abstract

We report an outbreak of severe acute respiratory syndrome coronavirus 2 501Y.V2 in a nursing home. All nonvaccinated residents (5/5) versus half of those vaccinated with BNT162b2 (13/26) were infected. Two of 13 vaccinated versus 4 of 5 nonvaccinated residents presented severe disease. BNT162b2 did not prevent the outbreak, but reduced transmission and disease severity.

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