Abstract
BACKGROUND: Auditory hallucinations affect 60%-80% of schizophrenia patients, often causing distress and functional impairment. Despite antipsychotic treatment, 30% remain resistant. Dysfunctional prefrontal-temporal connectivity has been found to be associated with these symptoms. Repetitive Transcranial Magnetic Stimulation (rTMS) is a neuromodulation technique that targets the dysfunctional area and is being used for treatment of persistent auditory hallucinations in Schizophrenia with mixed results. Continuous Theta Burst Stimulation (cTBS) is a novel neuromodulation technique that works on the principals of rTMS with similar or more robust clinical efficacy. CASES: We describe the cases of three patients where cTBS was applied. CONCLUSION: Significant improvement in auditory hallucinations was noticed in all three patients. While this evidence must be interpreted with caution, future studies on this topic with robust protocol to be conducted.