Generation and characterization of IMAGINi013-A, an induced pluripotent stem cell line generated from a healthy donor

IMAGINi013-A 的生成和表征,这是一种由健康供体产生的诱导性多能干细胞系

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作者:Céline Banal, Nathalie Lefort

Abstract

Human pluripotent stem cells are a powerful tool to study development, to model diseases or as cellular substrates for drug screening. We generated a human induced pluripotent stem cell (hiPSC) line from a healthy control donor. Peripheral blood mononuclear cells (PBMCs) from this donor were reprogrammed using integration-free Sendai virus. This cell line had normal karyotype, expressed pluripotency hallmarks and differentiated into the three primary germ layers.

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