Generation of a human induced pluripotent stem cell line KUMi006 from a patient with multiple myeloma
从多发性骨髓瘤患者体内生成人类诱导性多能干细胞系 KUMi006
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作者:Ji-Hyeon Hong, Ji-Hea Kim, Ka-Won Kang, Byung-Hyun Lee, Young Park, Byung-Soo Kim
| 期刊: | Stem Cell Research | 影响因子: | 0.800 |
| 时间: | 2022 | 起止号: | 2022 May:61:102767. |
| doi: | 10.1016/j.scr.2022.102767 | 种属: | Human |
| 研究方向: | 发育与干细胞、肿瘤 | 疾病类型: | 骨髓瘤 |
| 细胞类型: | 干细胞 | |
Abstract
In this study, we report the generation of a novel human induced pluripotent stem cell (hiPSC) line from bone marrow mononuclear cells of a patient with multiple myeloma, using an integrative Sendai virus vector. This pluripotent cell line has been shown to differentiate into three germ layers. Therefore, these induced pluripotent stem cells (iPSCs) will enable not only advances in cell therapy products but also the study of mechanisms.
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