L-Arginine Ameliorates High-Fat Diet-Induced Atherosclerosis by Downregulating miR-221
L-精氨酸通过下调 miR-221 改善高脂饮食引起的动脉粥样硬化
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作者：Hexi Zhang, Li Wang, Fei Peng, Xin Wang, Hui Gong
Conclusion
This research could provide potential therapies for the treatment of AS.
Results
The results suggested that L-arginine could prevent oxidized low-density lipoprotein-induced apoptosis in endothelial cells, which is associated with the downregulation of miR-221. Similar results were also observed in rat AS models.
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