Simple, sensitive and specific detection method for polystyrene nanoplastics in food matrix based on peptide-modified Fe(3)O(4)@Au magnetic nanoparticles

基于肽修饰的Fe(3)O(4)@Au磁性纳米粒子的食品基质中聚苯乙烯纳米塑料的简便、灵敏和特异的检测方法

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Abstract

Microplastics (MPs) and nanoplastics (NPs) are emerging hazardous pollutants that pose a significant threat to the global environment and human health. MPs and NPs have been detected in water sources and food products. Due to the wide variety of NPs, and low concentrations in environment and food samples, the rapid and selective detection of NPs still remains a challenge. Here, we prepared the peptide modified Fe(3)O(4)@Au magnetic nanoparticles as a selective probe to establish a simple, sensitive and specific method for polystyrene (PS) NPs detection. First, a layer of gold shell was in-situ grown on the surface of Fe(3)O(4) to provide more modification sites, and the PS binding peptide (PSBP) was then modified by Au-S bonds to construct a selective probe for PS NPs. Under optimized detection conditions, ultra-low concentration of PS could be quantitatively detected by simply monitoring the UV-vis absorption change of the probe. The peptide modified Fe(3)O(4)@Au probe (Fe(3)O(4)@Au-PSBP) showed excellent linearity in the range from 0 to 80 pg mL(-1) with the limit of detection (LOD) of 0.074 pg mL(-1). The method has been successfully applied in real samples, such as bottled water, salt and milk with the recoveries from 89.15 % to 110.91 %. The proposed Fe(3)O(4)@Au-PSBP is easily extendable to other types of NPs by simply replacing the peptide, showing great potential as a universal specific probe for sensitive and rapid detection of low concentration NPs in the actual samples.

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