Assays for Detecting Henipavirus Antibodies

检测亨尼巴病毒抗体的检测方法

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作者:Lin-Fa Wang, Shailendra Mani, Chee Wah Tan, Danielle E Anderson

Abstract

While molecular detection has increasingly become the detection method of choice for infectious diseases, antibody detection remains an important approach for diagnosis and surveillance. For henipaviruses, antibody detection methods such as ELISA and Western blot played a key role in the initial discovery of bats as the natural reservoir host. Here, we will describe three additional antibody detection methods (LIPS, Luminex, and pseudovirus systems), which can be used in most BSL2 laboratories without the need for live virus and a high containment BSL4 facility.

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