Abstract
The rapid global spread of Coronavirus disease 2019 (COVID-19) has seriously threatened human life and health. Effects of traditional Chinese medicine, Lianhua Qingwen, combined with western medicine remains controversial for treatment of COVID-19. Evidence to support use of Lianhua Qingwen in COVID-19 is lacking. In this study, we systematically reviewed literature on the use of Lianhua Qingwen in COVID-19, and we performed meta-analysis to assess the effect of Lianhua Qingwen in COVID-19 management. We found that when combined with western medicine in the treatment of COVID-19 patients, Lianhua Qingwen may shorten duration of fever, reduce adverse events, decrease rate of conversion to severe disease, and improve symptom recovery and chest radiographic signs of pneumonia.