Folate Receptor-Targeted Theranostic Nanoconstruct for Surface-Enhanced Raman Scattering Imaging and Photodynamic Therapy

叶酸受体靶向诊疗纳米结构用于表面增强拉曼散射成像和光动力治疗

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作者:Andrew M Fales, Bridget M Crawford, Tuan Vo-Dinh

Abstract

We report the synthesis of a folate receptor (FR)-targeted theranostic nanocomposite for surface-enhanced Raman scattering (SERS) imaging and photodynamic therapy (PDT). FR-specific SERS detection and PDT are demonstrated in vitro using two FR-positive cancer cell lines and one FR-negative cancer cell lines.

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