Abstract
We report a rare case of bilateral re-expansion pulmonary edema with delayed onset occurring 12-24 hours after pleural fluid drainage in a male patient in his eighties. Unlike the typical presentation, which occurs within 1-2 hours, this case involved bilateral lung involvement and a significantly delayed onset. This observation underscores the importance of close monitoring and heightened clinical vigilance following pleural drainage, particularly in elderly patients with multiple comorbidities. Our case highlights the importance of being aware of both common and uncommon complications associated with pleural drainage, underscoring the value of adhering to current clinical guidelines.