Abstract
OBJECTIVE: To analyze the trend of pathogenic specimen detection rate before antibiotic treatment in inpatients in Shandong Province from 2014 to 2023 and to provide a scientific basis for optimizing antibiotic management. METHODS: The time of antibiotic use and the time of pathogenic specimen collection for inpatients in each hospital were collected through the hospital information system, the test information system, and the mobile care system. The process data of specimen detection rate were calculated according to different time points: the pre-antibiotic treatment pathogenic detection rate, the detection rate within 12 h after antibiotic treatment, the detection rate within 24 h, and the detection rate before discharge. RESULTS: The detection rate of pre-antibiotic therapy pathogenicity specimens among inpatients in Shandong Province from 2014 to 2023 showed an overall increasing trend from 7.67 to 38.38%, while the pre-discharge detection rate increased from 32.84 to 67.48%; both differences were statistically significant (p < 0.01). The percentage of pathogenic samples sent for testing 0-12 h after antimicrobial drug treatment decreased from 26.74 to 25.10%, and the percentage sent 12-24 h after treatment decreased from 23.96 to 12.18%. CONCLUSION: The detection rate of pre-antibiotic therapy pathogenicity specimens among inpatients in Shandong Province showed an increasing trend from 2014 to 2023, but the number of people tested only 12 h after antibiotic therapy is still high and so needs to be focused on. This could be achieved by improving hospital information systems and increasing training.