Enantioselective total syntheses of six natural and two proposed meroterpenoids from Psoralea corylifolia

从补骨脂中对映选择性地全合成了六种天然和两种推测的半萜类化合物

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Abstract

The first enantioselective total syntheses of six natural and two proposed meroterpenoids isolated from Psoralea corylifolia have been achieved in 7-9 steps from 2-methylcyclohexanone. The current synthetic approaches feature a high level of synthetic flexibility, stereodivergent fashion and short synthetic route, thereby providing a potential platform for the preparation of numerous this-type meroterpenoids and their pseudo-natural products.

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