Competing C-H and C-F bond activation reactions of a fluorinated olefin at Rh: a fluorido vinylidene complex as an intermediate in an unprecedented dehydrofluorination step

氟代烯烃在铑上的竞争性CH和CF键活化反应:氟代乙烯基络合物作为前所未有的脱氟化氢步骤的中间体

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Abstract

The hydrofluoroolefin Z-1,3,3,3-tetrafluoropropene has been activated via an initial C-F bond activation and subsequent C-H bond activation using [Rh(H)(PEt(3))(3)] (1) or via C-H bond activation at [Rh(CH(3))(PEt(3))(3)] (8). In both cases the formation of [Rh{(E)-CF[double bond, length as m-dash]CHCF(3)}(PEt(3))(3)] (3) was observed. Importantly, the C-F activation product [Rh{(E)-CH[double bond, length as m-dash]CHCF(3)}(PEt(3))(3)] (2) reacts in the presence of Z-1,3,3,3-tetrafluoropropene into 3. The latter converted into [Rh(C[triple bond, length as m-dash]CCF(3))(PEt(3))(3)] (6) by an unprecedented dehydrofluorination reaction, presumably via a vinylidene complex as intermediate. When the carbonyl complex [Rh(C[triple bond, length as m-dash]CCF(3))(CO)(PEt(3))(3)] (12) was treated with an excess of NEt(3)·3HF or HBF(4) at low temperature, the formation of the phosphonioalkenyl compounds [Rh{(Z)-C(PEt(3))[double bond, length as m-dash]CHCF(3)}(CO)(PEt(3))(2)]X (X = F(HF) (x) , BF(4)) (13) was observed. The formation of 13 can be explained by an attack of PEt(3) at the electrophilic α-carbon atom of an intermediate vinylidene complex. The employment of P(i)Pr(3) derivatives as model compounds allowed for the isolation of the unique fluorido vinylidene complex trans-[Rh(F)([double bond, length as m-dash]C[double bond, length as m-dash]CHCF(3))(P(i)Pr(3))(2)] (16), which in the presence of PEt(3) transforms into [Rh(C[triple bond, length as m-dash]CCF(3))(PEt(3))(3)] (6).

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