Abstract
The 9-valent human papillomavirus vaccine (9vHPV) protects against 9 HPV genotypes linked to cervical cancer and genital warts. While rare, HPV vaccines may trigger autoimmune reactions. Alopecia areata (AA) is a chronic autoimmune disease that causes non-scarring alopecia. Similarly, the development of AA induced by vaccines is a rare occurrence. This report presents a case of a healthy female who developed alopecia universalis after 9vHPV vaccination, aiming to document the event, share treatment, and highlight the need for prompt medical attention.