Comparison of Right Ventricle Morphological and Mechanical Characteristics for Healthy and Patients with Tetralogy of Fallot: An In Vivo MRI-Based Modeling Study

健康人和法洛四联症患者右心室形态和力学特征的比较:一项基于体内MRI建模的研究

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Abstract

Patients with repaired tetralogy of Fallot (TOF) account for the majority of cases with late onset right ventricle failure. Comparing TOF patients with healthy people may provide information to address this challenge. Cardiac magnetic resonance (CMR) data were obtained from 16 TOF patients (patient group, PG) and 6 healthy volunteers (healthy group, HG). At begin-of-ejection, better patient group (n=5, BPG) stress was very close to HG stress (54.7±38.4 kPa vs. 51.2±55.7 kPa, p=0.6889) while worse patient group (n=11, WPG) stress was 84% higher than HG stress (p=0.0418). Stress may be used as an indicator to differentiate BPG patients from WPG patients, with further validations.

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