Abstracts from the 8th International Congress of the Asia Pacific Society of Infection Control (APSIC): Bangkok, Thailand. 12-15 February 2017

第八届亚太感染控制学会（APSIC）国际大会摘要：泰国曼谷，2017年2月12-15日

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作者：Teo,Jocelyn Qi-Min,Candra,Samuel Rocky,Lee,Shannon Jing-Yi,Chia,Shannon Yu-Hng,Leck,Hui,Tan,Ai-Ling,Neo,Hui-Peng,Leow,Kenneth Wei-Liang,Cai,Yiying,Ee,Pui Lai Rachel,Lim,Tze-Peng,Lee,Winnie,Kwa,Andrea Lay-Hoon,Sutthiruk,Nantanit,Botti,Mari,Considine,Julie,Driscoll,Andrea,Hutchinson,Ana,Malathum,Kumthorn,Cucunawangsih,Cucunawangsih,Wiwing,Veronica,Puspitasari,Vivien,Shanmugakani,Rathina Kumar,Akeda,Yukihiro,Kodera,Takuya,Santanirand,Pitak,Tomono,Kazunori,Yamanaka,Takayuki,Moriuchi,Hiroyuki,Kitajima,Hiroyuki,Horikoshi,Yuho,Lavrinenko,Alyona,Azizov,Ilya,Tabriz,Nurlan,Kozhamuratov,Margulan,Serbo,Yekatherine,Yang,Dahae,Lee,Woonhyoung,Bae,Il Kwon,Lee,Jae Hyun,Lee,Hyukmin,Kim,Jung Ok,Jeong,Seok Hoon,Lee,Kyungwon,Peremalo,Thiba,Madhavan,Priya,Hamzah,Sharina,Than,Leslie,Wong,Eng Hwa,Desa,Mohd Nasir Mohd,Ng,Kee Peng,Geronimo,Marionne,Tayzon,Maria Fe,Maño,Maria Jesusa,Chow,Angela,Hon,Pei-Yun,Win,Mar-Kyaw,Ang,Brenda,Leo,Yee-Sin,Chow,Angela,Hon,Pei-Yun,See,Tina,Ang,Brenda,Marin,Rocio Alvarez,de Sousa,Marta Aires,Kieffer,Nicolas,Nordmann,Patrice,Poirel,Laurent,Laochareonsuk,Wison,Petyu,Sireekul,Wanasitchaiwat,Pawin,Thana,Sutasinee,Bunyaphongphan,Chollathip,Boonsomsuk,Woranan,Maneepongpermpoon,Pakpoom,Jamulitrat,Silom,Sureshkumar,Dorairajan,Supraja,Kalyanaraman,Sharmila,Soundararajan,Cucunawangsih,Cucunawangsih,Setiawan,Benny,Lumbuun,Nicolaski,Nakayama,Haruo,Ota,Toshiko,Shirane,Naoko,Matuoka,Chikako,Kodama,Kentaro,Ohtsuka,Masanobu,Bacolcol,Silverose Ann Andales,Velmonte,Melecia,Alde,Allan,Chavez,Keithleen,Esteban,Arlene Joy,Lee,Aisa Jensen,Hsieh,Tai-Chin,Shio-ShinJean,Huang,Huey-Jen,Huang,Shu-Ju,Huang,Yu-Huan,Cheng,Pei-Chen,Yu,Su-Fang,Tsao,Shih-Ming,Lee,Yuan-Ti,Li,Chien-Feng,Lu,Min-Chi,Pruetpongpun,Nattapol,Khawcharoenporn,Thana,Damronglerd,Pansachee,Suwantarat,Nuntra,Apisarnthanarak,Anucha,Rutjanawech,Sasinuch,Cushinotto,Lisa,McBride,Patty,Williams,Harding Jr,Liu,Hans,Hang,Phan Thi,Anh,Dinh Pham Phuong,Le,Ngai,Khu,Dung,Nguyen,Lam,Castillo,Roel Beltran,Sureshkumar,Dorairajan,Gopalakrishnan,Ram,Ramasubramanian,Venkatasubramanian,Sreevidya,Subramanian,Jayapradha,Ranganathan,Umetsu,Atsushi,Noda,Tetsuhiro,Hashimoto,Kenyuu,Hayashi,Akihiro,Kabashima,Mikie,Jadczak,Ursula,Elvelund,Knut,Johnsen,Marit,Borgen,Bente,Lingaas,Egil,Mao,Chia-Hua,Chang,Fu-Chieh,Liu,Chang-Pan,Chao,Ru-Hui,Chang,Fu-chieh,Liu,Chang-pan,Pawapotako,Junpen,Prasertpan,Chadanan,Malaihuan,Wantanee,Uirungroj,Phisit,Prasertpan,Chadanan,Saenjum,Chalermpong,Ouirungrog,Teerapat,Uirungroj,Phisit,Borrell,Sue,Bass,Pauline,Worth,Leon,Xian-li,Zhao,Xiao-long,Li,Xue-hua,Yao,Wei,Ren,Zeng,Zhang Xia,Kong,Man Ying,Lai,Christopher Koon Chi,Lee,Suet Yi,Tsang,Ngai Chong,O’Donoghue,M M,Boost,M V,Suen,L K P,Siu,G K,Mui,K W,Lai,C K C,Tsang,D N C,Sato,Yuka,Tateishi,Mariko,Mihashi,Mutsuko,Flor,Jose Paulo,Bautista,Marko,De Roxas,V Jay,Vergara,Justine,Añonuevo,Nicolo Andrei,Kwek,Marion,Acuin,Jose,Sanchez,Anna Josea,Bathan,Avel,Jantan,Jamilah Binte,Guek,Chua Chor,Kian,Eu Chiow,Pirido,Pampe Anak,Aron,Nur Fadilah Binte Mohd,Estacio,Leah May,Palana,Francis Alvarez,Gracia,Michelle,Shamsuddin,Nur Syafiqah Binte,Castro,Kersten Timbad,Baloria,Madonna,Adam,Faezah Binte,Wei,Zhang,Fong,Poh Bee,Kalisvar,Marimuthu,Chow,Angela,Ang,Brenda,Chuang,I-Ju,Yi-ChunCho,Chiu,Yu-Fen,Chen,Lung-Chih,Lin,Yi-Chun,Dong,Shao-Xing,Lee,Yi-Chieh,Kuan,Hui-Chen,Lin,Hsin-Hua,Chi,Chia-Chun,Lu,Chin-Te,Chang,Fu-chieh,Liu,Chang-pan,Ya-Fen,Tang,Li-Hsiang,Su,Jien-Wei,Liu,Chao,Hsuehlan,ChangChien,PinRu,Chen,WeiFang,Lai,ChungHsu,Ara,Lutfe,Mowla,Syed Mohammad Niaz,Vashkar,Shaikh Mahmud Kamal,Chan,Wai Fong,ChunYau,Mabel Yin,LingChong,Karen Kam,OnLi,Tze,Kaur,Rajwinder,Yan,Ng Po,Chiu,Gloria Chor Shan,Cheung,Christina W Y,Ching,Patricia T Y,Ching,Radley H C,Lam,Conita H S,Kan,C H,Lee,Shirley S Y,Chen,C P,Chan,Regina F Y,Leung,Annie F Y,Wong,Isadora L C,Lam,S S,Chan,Queenie W L,Chan,Cecilia,Kaur,Rajwinder,Nematian,Seyed Sadeq Seyed,Palenik,Charles John,Askarian,Mehrdad,Nematian,Seyed Sadeq Seyed,Palenik,Charles John,Hatam,Nahid,Askarian,Mehrdad,Nakamura,Itaru,Fujita,Hiroaki,Tsukimori,Ayaka,Kobayashi,Takehito,Sato,Akihiro,Fukushima,Shinji,Matsumoto,Tetsuya,Flor,Jose Paulo,Añonuevo,Nicolo Andrei,Bautista,Marko,Vergara,Justine,De Roxas,V James,Kwek,Marion,Flor,Jose Paulo,Bautista,Marko,Vergara,Justine,De Roxas,V James,AndreiAñonuevo,Nicolo,Kwek,Marion,Ho,Yeng May,Kum,Jia Qi,Poh,Bee Fong,Marimuthu,Kalisvar,Ang,Brenda,Liu,Tzu-Yin,Chu,Sin-Man,Chen,Hui-Zhu,Chen,Tun-chieh,Chen,Yichun,Tsao,Ya-Ching,Skuntaniyom,Sumawadee,Malathum,Kumthorn,Tipluy,Pirawadee,Paengta,Sangwan,wongsaen,Ratchanee,thanomphan,Sutthiphun,Tariyo,Samettanet,Thongchuea,Buachan,Khamfu,Pattama,Thanomphan,Sutthiphan,Songtaweesin,Wipaporn Natalie,Anugulruengkit,Suvaporn,Samransamruajkit,Rujipat,Sosothikul,Darintr,Tansrijitdee,Ornanong,Nakphunsung,Anry,Srimuan,Patchareeyawan,Sophonphan,Jirachaya,ThanyaweePuthanakit,Payuk,Kunyanut,Picheansathian,Wilawan,Viseskul,Nongkran,DeNardo,Elizabeth,Leslie,Rachel,Cartner,Todd,Barbosa,Luciana,Werner,Heinz-Peter,Brill,Florian H H,Kawagoe,Julia Yaeko,De Nardo,Elizabeth,Wilson,Sarah Edmonds-,Macinga,David,Mays-Suko,Patricia,Duley,Collette,Hang,Phan Thi,Hang,Tran Thi Thuy,Hanh,Tran Thi My,Gordon,Christopher,Sureshkumar,Dorairajan,Durairaj,Roopa,Rohit,Anusha,Saravanakumar,Saujanya,Hemalatha,Jothymani,Hirano,Ryuichi,Sakamoto,Yuichi,Yamamoto,Shoji,Tachibana,Naoki,Miura,Miho,Hieda,Fumiyo,Sakai,Yoshiro,Watanabe,Hiroshi,Velmonte,Melecia,Bacolcol,Silverose Ann,Alde,Allan,Chavez,Keitleen,Esteban,Arlene Joy,Lee,Aisa Jensen,Chow,Angela,Lim,Jia-Wei,Hon,Pei-Yun,Hein,Aung-Aung,Tin,Grace,Lim,Vanessa,Ang,Brenda,Chow,Angela,Hein,Aung-Aung,Lim,Jia-Wei,Hon,Pei-Yun,Lim,Vanessa,Tin,Grace,Ang,Brenda,Chow,Angela,Tin,Grace,Hein,Aung-Aung,Lim,Vanessa,Lim,Jia-Wei,Hon,Pei-Yun,Ang,Brenda,Chao,Huwi-chun,Yeh,Chiu-Yin,Lo,Mei-feng,Chao,Huwi-chun,Piwpong,Chonlada,Rajborirug,Songyos,Preechawetchakul,Ploypailin,Pruekrattananapa,Yada,Sangsuwan,Tharntip,Jamulitrat,Silom,Wongsaen,Ratchanee,Paengta,Sungwan,Nilchon,Napatnun,Thanompan,Sutthipun,Tariyo,Samattanet,Le,Ngai,Khu,Dung,Kolesnichenko,Svetlana,Azizov,Ilya,Lavrinenko,Alyona,Tishkambayev,Yerbol,Lavrinenko,Alyona,Azizov,Ilya,Tishkambayev,Yerbol,Alibecov,Asylkhan,Kolesnichenko,Svetlana,Serbo,Yekaterina,Nam,Youngwon,Park,Jae Hyeon,Hong,Yun Ji,Kim,Taek Soo,Park,Jeong Su,Park,Kyoung Un,Kim,Eui-Chong,Aziegbemhin,Samuel Abumhere,Enabulele,Onaiwu,Tung,Yao-Shen,Chen,An-Chi,Huang,Shen-Min,Yang,Yui-Yein,Wu,Li-Hung,Lin,Chin-cheng,Chang,Fu-chieh,Liu,Chang-pan,Lien,Tzu Hao,Chang,Jia Hao,Huang,Yu Shan,Chen,Yi Shun,Saenjum,Chalermpong,Sirilun,Sasithorn,Ouirungrog,Teerapat,Ouirungroj,Phisit,Trakulsomboon,Suwanna,Prasajak,Patcharee,Kwok,Maryanne W N,Ng,Lady S H,Wong,Lindy M T,Poon,Lenina S L,Lai,Mary K L,Cheng,Holly H S,Fong,S K,Leung,Cindy F Y,Hasegawa,Jumpei,Shirakawa,Hiroki,Wakai,Sachiko,Mieno,Makiko,Hatakeyama,Shuji,Tateishi,Mariko,Mihashi,Mutsuko,Sato,Yuka,Saenjum,Chalermpong,Deeudom,Manu,Tharavichitkul,Prasit,Ouirungrog,Teerapat,Ouirungroj,Phisit,Chinniah,Terrence,Tan,Jackson,Prabu,Kavitha,Alam,Sartaj,Wynn,Aung Kyaw,Ahmad,Rashidah,Sidek,Amalina,Samsuddin,Dg Azizah,Ajis,Noraini,Ahmad,Aliyah,Magon,Susylawathi,Chu,Boon,Kuang,Jiqiu,Gao,Yan,Wang,Shoujun,Hao,Yunxiao,Liu,Rong,Li,Dongmei,Wang,Hui,Yan,Ng Po,Nishio,Hisanori,Mori,Hitomi,Morokuma,Yoshiko,Yamada,Takaaki,Kiyosuke,Makiko,Yasunaga,Sachie,Toyoda,Kazuhiro,Shimono,Nobuyuki,Babenko,Dmitriy,Turmuhambetova,Anar,Cheşcă,Antonella,Toleman,Mark A,Babenko,Dmitriy,Turmuhambetova,Anar,Cheşcă,Antonella,Toleman,Mark A,Babenko,Dmitriy,Turmuhambetova,Anar,Azizov,Ilya,Cheşcă,Antonella,Toleman,Mark A,Akhmaltdinova,Lyudmila L,Turmuhambetova,Anar,Cheşcă,Antonella,Babenko,Dmitriy,Magsakay,Mark Albert,Macatibag,Angelo,Tayzon,Maria Fe,Lerios,Jeannica Kriselle,Azizov,Ilya,Lavrineko,Alyona,Babenko,Dmitry,Sheck,Eugene,Edelstein,Mikhail,Liu,Tzu-Yin,Li,Lih-Yue,Chan,Chiung-Wen,Pan,Hui-Chuan,Chen,Tun-chieh,Vanishakije,Wipa,Jaikampun,Warisra,Cheng,Pei-Chen,Huang,Huey-Jen,Huang,Shu-Ju,Huang,Yu-Huan,Li,Su-Yin,Yu,Su-Fang,Li,Jian-Feng,Wu,Yu-Ping,Lee,Yuan-Ti,Lin,Chiao-Hui,Chang,Ping-Chin,Tariyo,Samatanet,Paengta,Sangwan,Wongsaen,Ratchanee,Thanompan,Suttsiphan,Skuntaniyom,Sumawadee,Malathum,Kumthorn,Sukkra,Suchada,Zaman,Khalequ,Zaman,Sheikh Farzana,Zaman,Farzana,Aziz,Asma,Faisal,Sayeed-Bin,Traskine,Magali,Ruiz-Guiñazú,Javier,Borys,Dorota,Zaman,Khalequ,Zaman,Sheikh Farzana,Zaman,Farzana,Aziz,Asma,Faisal,Sayeed-Bin,Traskine,Magali,Ruiz-Guiñazú,Javier,Borys,Dorota,Lam,Wendy Wai Yee,Chow,May,Choy,Lucy,Kam,Joseph,Salleh,Sharifah Azura,Yacob,Razila,Yusof,Siti Rokiah,Jalil,Nordiah Awang,Flor,Jose Paulo,Añonuevo,Nicolo Andrei,Bautista,Marko,De Roxas,V Jay,Vergara,Justine,Millan,Maria Lourdes,Kwek,Marion,Acuin,Jose Lito,Lee,Aisa Jensen,Velmonte,Melecia A,Bacolcol,Silverose Ann A,Alde,Allan,Chavez,Keitleen,Esteban,Arlene Joy,Ting,Ching-I,Dissayasriroj,Sunisa,Chinniah,Terrence Rohan,Prabu,Kavitha,Ahmad,Rashidah,Magon,Susylawathi,DiniSuhaimi,Jauharatud,Mirasin,Aizzuddin,Morni,Nurul,Chu,Boon,Samsuddin,Azizah,Ahmad,Aliyah,Sidek,Amalina,Ajis,Noraini,AbuBakar,Amalina,Shafiee,Amanie,Safar,Julaini,Yan,Ng Po,Annie,Leung,Ling,Fung Yuk,Edna,Lau,Kristine,Luk,Shinomiya,Satoshi,Yamamoto,Kumiko,Kjiwara,Kayoko,Yamaguchi,Mitsuhiro,Chow,Angela,Tin,Grace,Zhang,Wei,Hon,Pei-Yun,Poh,Bee-Fong,Marimuthu,Kalisvar,Ang,Brenda,Chan,Ming-Chin,Wang,Chih-Chien,Huang,Shu-Ju,Huang,Huey-Jen,Yu,Su-Fang,Huang,Huan-Yu,Cheng,Pei-Chen,Li,Jian-Feng,Lee,Yuan-Ti,Lai,Chiung-Ling,Lu,Min-Chi,Kosol,Sajeerat,Sakolwirat,Wantana,Paepong,Patchanee,Jansanga,Sawalee,Jaisamoot,Pattarin,Thongnuanual,Nuttha,Srithong,Chittima,Somsakul,Somporn,Malathum,Kumthorn,Plongpunth,Sutima,Punpop,Mukkapon,Malathum,Porntip,Malathum,Kumthorn,Thanomphan,Sutthiphan,Wongsaen,Ratchanee,Peautiwat,Kulada,boon kirdram,Nattawipa,Picheansathian,Wilawan,Klunklin,Pimpaporn,Samethadka,Geetha,Suzuki,Naoko,Asada,Hitomi,Katayama,Masao,Komano,Atsushi,Sato,Akihiro,Nakamura,Itaru,Watanabe,Hidehiro,Matsumoto,Tetsuya,Seo,Hye Kyung,Hwang,Joo-Hee,Shin,Myoung Jin,Kim,Su Young,Kim,Eu Suk,Song,Kyoung-Ho,Kim,Hong Bin,Un,Lai-Si,Vong,Choi-Ian,Flor,Jose Paulo,Añonuevo,Nicolo Andrei,Bautista,Marko,De Roxas,V James,Vergara,Justine,Kwek,Marion,Koh,Jocelyn,Agustinus,Sherly,Hassan,Rozita Bte Abu,Thinn,Yin Phyu,Ng,Benjamin,Tun,Soe Pyae,Ha,Su Mon Thi,Xiaoting,Xue,Li,Lin,Chuang,Leyland,Niroshika,Attanayaka Mudiyanselage Chulani,Perera,Kaluarachchige Anoma Kaluarachchi,Fernando,Dimingo Kankanamalage Diana Grace,Hemamala,Bodhipakshage Rohini,Yeh,Chiu-yin,Chao,Huwi-chun,Yang,Hui-Chun,Chiu,Hsiang-Ju,Shih,Ya-Ling,Chien,Yu-Shan,Lin,Wan-Yi,Pan,Chia-Yun,Chang,Ying-Yun,Yea,Chiu-Yuch,Chu,Ming-Hsien,Lee,Li-Chu,Chiu,Hsiang-Ju,Shih,Ya-Ling,Yang,Hui-Chun,Yu-Hsiu,Lin,Siao-Pei,Guo,Pak-On,Leung,Mei-Fe,Sie,Jyh-Jou,Chen,Yu-Hsiu,Lin,Yong-Yuan,Chang,Kuo,Shu-Yuan,Lin,Yu-Hsiu,Zhang,Ji-Sheng,Leung,Pak-On,Sie,Mei-Fe,Chen,Jyh-Jou,Chen,Yan-Ru,Lin,Yu-Hsiu,Chen,Ying-Ling,Taou,Chi-Fen,Chen,Hsiao-Shan,Tang,Hung-Jen,Chen,Shin Yu,Chen,Yin Yin,Der Wang,Fu,Shih,Tzu-Ping,Chen,Chin-Yu,Chen,Su-Jung,Wu,Mei-chi,Yang,Wan-ju,Chou,Mei-ling,Yu,Man-Ling,Li,Li-Chu,Chu,Cheng-Wei,Tsou,Wen-Hao,Wu,Wen-Chih,Cheng,Wen-Chi,Sun,Cho-Ching,Shih,Tzu-Ping,Chen,Chin-Yu,Lu,Shu-Hua,Chen,Su-Jung,Yang,Hsin-Ling,Lu,Cheng-Yu,Yu,Man-Ling,Li,Li-Chu,Chu,Cheng-Wei,Tsou,Wen-Hao,Wu,Wen-Chih,Cheng,Wen-Chi,Sun,Cho-Ching,Hirunprapakorn,Nitchawan,Malathum,Kumthorn,Apivanich,Sirilux,Pornmee,Ttipakorn,Beowsomboon,Chonnikarnt,Rajborirug,Songyos,Pruekrattananapa,Yada,Sangsuwan,Tharntip,Jamulitrat,Silom,Kumkoom,Itthaporn,Kasatpibal,Nongyao,Chitreecheur,Jittaporn,Kasatpibal,Nongyao,Whitney,JoAnne D,Saokaew,Surasak,Kengkla,Kirati,Heitkemper,Margaret M,Apisarnthanarak,Anucha,Muntajit,Thanomvong,Apivanich,Siriluk,Malathum,Kumthorn,Somsakul,Somporn,Phan,Hang Thi,Dinh,Anh Pham Phuong,Nguyen,Tuyet Thi Kim
期刊：Antimicrobial Resistance and Infection Control影响因子：4.400
时间：2017起止号：2017;6(Suppl 2):27
doi：10.1186/s13756-017-0184-1

Abstract

BACKGROUND: Candidemia is a common cause of nosocomial bloodstream infections, resulting in high morbidity and mortality. This study was conducted to describe the epidemiology, species distribution, antifungal susceptibility patterns and outcomes of candidemia in a large regional tertiary referral hospital. METHODS: A retrospective surveillance study of patients with candidemia was conducted at Singapore General Hospital between July 2012 and December 2015. In addition, incidence densities and species distribution of candidemia episodes were analysed from 2008 to 2015. RESULTS: In the period of 2012 to 2015, 261 candidemia episodes were identified. The overall incidence was 0.14/1000 inpatient-days. C. glabrata (31.4%), C. tropicalis (29.9%), and C. albicans (23.8%) were most commonly isolated. The incidence of C. glabrata significantly increased from 2008 to 2015 (Coefficient 0.004, confidence interval 0-0.007, p = 0.04). Fluconazole resistance was detected primarily in C. tropicalis (16.7%) and C. glabrata (7.2%). fks mutations were identified in one C. albicans and one C. tropicalis. Candidemia episodes caused by C. tropicalis were more commonly encountered in patients with haematological malignancies (p = 0.01), neutropenia (p < 0.001) and higher SAPS II scores (p = 0.02), while prior exposure to echinocandins was associated with isolation of C. parapsilosis (p = 0.001). Echinocandins (73.3%) were most commonly prescribed as initial treatment. The median (range) time to initial treatment was 1 (0-9) days. The 30-day in-hospital mortality rate was 49.8%. High SAPS II score (Odds ratio, OR 1.08; 95% confidence interval, CI 1.05-1.11) and renal replacement therapy (OR 5.54; CI 2.80-10.97) were independent predictors of mortality, while drain placement (OR 0.44; CI 0.19-0.99) was protective. CONCLUSIONS: Decreasing azole susceptibilities to C. tropicalis and the emergence of echinocandin resistance suggest that susceptibility patterns may no longer be sufficiently predicted by speciation in our institution. Candidemia is associated with poor outcomes. Strategies optimising antifungal therapy, especially in the critically-ill population, should be explored.

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