A natural BACE1 and GSK3β dual inhibitor Notopterol effectively ameliorates the cognitive deficits in APP/PS1 Alzheimer's mice by attenuating amyloid-β and tau pathology

天然的BACE1和GSK3β双重抑制剂诺托普特罗通过减轻淀粉样蛋白β和tau蛋白病理，有效改善APP/PS1阿尔茨海默病小鼠的认知缺陷。