Exploring the bi-directional relationship between pancreatic cancer and diabetes mellitus: a retrospective study

探讨胰腺癌与糖尿病的双向关系:一项回顾性研究

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Abstract

OBJECTIVE: To explore the bi-directional between pancreatic cancer (PC) and diabetes mellitus (DM); focusing on the prevalence, temporal association and impact on survival outcomes. METHODS: A retrospective audit of pancreatic cancer patients from the institutional clinical database (CaNISC) between January 2012 and April 2018. RESULTS: A total of 131 patients were analysed, 58 patients carried a diagnosis of diabetes mellitus. The median overall survival for diabetes mellitus patients was 12.0 months (95 CI, 5.9 to 18.1 months) in comparison to 13.0 months (95% CI, 8.6 to 17.3 months) in non-diabetes mellitus patients (p = 0.334). CONCLUSION: There was no significant difference in the overall survival between DM and non-DM patients.

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