Resistance/susceptibility to lethal Sendai virus infection genetically linked to a mucociliary transport polymorphism

对致命性仙台病毒感染的抵抗力/易感性与粘液纤毛转运多态性存在基因关联

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Abstract

Linkage was tested between a mucociliary transport polymorphism and resistance/susceptibility to lethal Sendai virus infection in segregant hybrid mice of C57BL/6J and DBA/2J parents. The distribution of paired phenotypes for tracheal mucociliary transport rates and susceptibility to lethal Sendai virus infection in 171 F1 X DBA/2J mice showed strong interaction of the parental phenotypes.

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