Capsular Typing Method for Streptococcus agalactiae Using Whole-Genome Sequence Data

利用全基因组序列数据对无乳链球菌进行荚膜分型的方法

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Abstract

Group B streptococcus (GBS) capsular serotypes are major determinants of virulence and affect potential vaccine coverage. Here we report a whole-genome-sequencing-based method for GBS serotype assignment. This method shows strong agreement (kappa of 0.92) with conventional methods and increased serotype assignment (100%) to all 10 capsular types.

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