In Situ Electrospinning Iodine-Based Fibrous Meshes for Antibacterial Wound Dressing

原位静电纺丝碘基纤维网用于抗菌伤口敷料

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作者:Guo-Sai Liu, Xu Yan, Fang-Fang Yan, Fu-Xing Chen, Long-Yun Hao, Shao-Juan Chen, Tao Lou, Xin Ning, Yun-Ze Long

Abstract

For effective application of electrospinning and electrospun fibrous meshes in wound dressing, we have in situ electrospun poly(vinyl pyrrolidone)/iodine (PVP/I), PVP/poly(vinyl pyrrolidone)-iodine (PVPI) complex, and poly(vinyl butyral) (PVB)/PVPI solutions into fibrous membranes by a handheld electrospinning apparatus. The morphologies of the electrospun fibers were examined by SEM, and the hydrophobicity, gas permeability, and antibacterial properties of the as-spun meshes were also investigated. The flexibility and feasibility of in situ electrospinning PVP/I, PVP/PVPI, and PVB/PVPI membranes, as well as the excellent gas permeabilities and antibacterial properties of the as-spun meshes, promised their potential applications in wound healing.

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