Abstract
Inflammasomes are massive intracellular multiprotein signaling complexes produced in the cytosolic compartment. Tumor etiology involves dysregulation of NLRP3 inflammasome activation. Current studies are being conducted to ascertain the effectiveness and safety of oral nutrient solution supplementation in patients with esophageal cancer based on the current understanding of the role of the NLRP3 inflammasome in possible cancer promotion and therapy. This study examines how oral nutrient solution supplement therapy affects patients receiving radiotherapy and chemotherapy for esophageal cancer in terms of nutrition, physical composition, quality of life, psychology, prognosis, and survival. A total of 120 patients with esophageal cancer admitted to our hospital from March 2020 to January 2021 were selected for the current study. The selected 120 patients are divided into nutritional supplement and traditional groups according to the random number table method, with 60 cases in each group. The nutritional supplement group received an oral nutritional solution, whereas the conventional group received the ordinary dietary intervention. Since radiotherapy can potentially damage healthy tissue with short- and long-term negative effects. Inflammatory reactions are a common component of adverse effects of early and late ionizing radiation. Oral nutrient solution supplement therapy for patients with esophageal cancer after radiotherapy and chemotherapy can significantly improve the levels of blood nutrients, later physical components, and quality of life of patients.