Effects of Cardiac Rehabilitation on Cardiac Function and Quality of Life in Patients with Ischemic Nonobstructive Coronary Artery Disease and Diabetes Mellitus

心脏康复对缺血性非阻塞性冠状动脉疾病合并糖尿病患者心脏功能和生活质量的影响

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Abstract

OBJECTIVE: To investigate the effect of cardiac rehabilitation on the quality of life in patients with ischemic and nonobstructive coronary artery disease complicated with diabetes mellitus. METHODS: From January 2020 to June 2021, 100 patients with ischemic nonobstructive coronary heart disease complicated with diabetes were randomly divided into the control group (n = 50). The routine drug therapy observation group (50 cases) was treated with routine drugs combined with cardiac rehabilitation at 6 months for 1 course. The curative effect, cardiac function, 6 min walking distance (6MWD), cardiopulmonary exercise test (CPFT) index, SF-36 Health Status Survey Scale, and quality of life score were compared between the two groups. RESULTS: The total effective rate of the observation group was significantly higher than that of the control group (P < 0.05). After treatment, there was no significant change in cardiac function and 6MWD in the control group. The left ventricular ejection fraction and 6MWD in the observation group were significantly higher/longer than those before treatment and the control group (all P < 0.05). After treatment, the indexes of CPET in the two groups were improved in varying degrees. The forced vital capacity and oxygen uptake of anaerobic valve in the observation group were significantly higher than those in the control group (all P < 0.05). After treatment, the scores of the SF-36 in both groups were improved in varying degrees. The physiological function, general health, energy, mental health, and total scores of the observation group were significantly higher than those of the control group (all P < 0.05). CONCLUSION: Cardiac rehabilitation can significantly improve the cardiorespiratory function, exercise ability, and quality of life in patients with ischemic and nonobstructive coronary artery disease complicated with diabetes mellitus.

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