Abstract
Nonnegative sparse representation has become a popular methodology in medical analysis and diagnosis in recent years. In order to resolve network degradation, higher dimensionality in feature extraction, data redundancy, and other issues faced when medical images parameters are trained using convolutional neural networks. Lung tumors in chest CT image based on nonnegative, sparse, and collaborative representation classification of DenseNet (DenseNet-NSCR) are proposed by this paper: firstly, initialization parameters of pretrained DenseNet model using transfer learning; secondly, training DenseNet using CT images to extract feature vectors for the full connectivity layer; thirdly, a nonnegative, sparse, and collaborative representation (NSCR) is used to represent the feature vector and solve the coding coefficient matrix; fourthly, the residual similarity is used for classification. The experimental results show that the DenseNet-NSCR classification is better than the other models, and the various evaluation indexes such as specificity and sensitivity are also high, and the method has better robustness and generalization ability through comparison experiment using AlexNet, GoogleNet, and DenseNet-201 models.