The Mediating Effect of Cytokines on the Association between Fungal Sensitization and Poor Clinical Outcome in Asthma

细胞因子在真菌致敏与哮喘不良临床预后之间的关联中的介导作用

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作者:Ching-Hsiung Lin, Yi-Rong Li, Chew-Teng Kor, Sheng-Hao Lin, Bin-Chuan Ji, Ming-Tai Lin, Woei-Horng Chai

Conclusion

IL-17A is a potential mediator to link Candida albicans sensitization and ED visits for asthma. We suggest that patients with fungal sensitization, such as Candida albicans, have poorer outcomes associated with Th17-mediated immune response rather than Th2.

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