The Mediating Effect of Cytokines on the Association between Fungal Sensitization and Poor Clinical Outcome in Asthma
细胞因子在真菌致敏与哮喘不良临床预后之间的关联中的介导作用
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作者:Ching-Hsiung Lin, Yi-Rong Li, Chew-Teng Kor, Sheng-Hao Lin, Bin-Chuan Ji, Ming-Tai Lin, Woei-Horng Chai
| 期刊: | Biomedicines | 影响因子: | 3.900 |
| 时间: | 2022 | 起止号: | 2022 Jun 19;10(6):1452. |
| doi: | 10.3390/biomedicines10061452 | 研究方向: | 信号转导、免疫 |
| 疾病类型: | 哮喘 | 细胞类型: | 其它细胞 |
Conclusion
IL-17A is a potential mediator to link Candida albicans sensitization and ED visits for asthma. We suggest that patients with fungal sensitization, such as Candida albicans, have poorer outcomes associated with Th17-mediated immune response rather than Th2.
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