Enhanced insulin sensitivity associated with provision of mono and polyunsaturated fatty acids in skeletal muscle cells involves counter modulation of PP2A

与骨骼肌细胞中单不饱和脂肪酸和多不饱和脂肪酸的供应相关的胰岛素敏感性增强涉及 PP2A 的反向调节

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作者:Francesca Nardi, Christopher Lipina, David Magill, Rima Hage Hassan, Eric Hajduch, Alexander Gray, Harinder S Hundal

Conclusions/interpretation

Beneficial gains in insulin sensitivity and the ability of unsaturated fatty acids to oppose palmitate-induced insulin resistance in muscle cells may partly be accounted for by counter-modulation of PP2A.

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