Flavin Adenine Dinucleotide Depletion Caused by electron transfer flavoprotein subunit alpha Haploinsufficiency Leads to Hepatic Steatosis and Injury in Zebrafish
电子转移黄素蛋白亚基α单倍体不足引起的黄素腺嘌呤二核苷酸耗竭导致斑马鱼肝脂肪变性和损伤
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作者：Ki-Hoon Park, Monika Gooz, Zhi-Wei Ye, Jie Zhang, Gyda C Beeson, Don C Rockey, Seok-Hyung Kim
Conclusion
FAD depletion caused by etfa haploinsufficiency plays a key role in hepatic steatosis and oxidative stress-mediated hepatic injury in adult zebrafish. This raises the possibility that people with ETFA haploinsufficiency have a high risk for developing liver disease.
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