Post-transplant lymphoproliferative disorder: case report and review of susceptibility to EBV in the Scottish adult renal transplant pool

移植后淋巴增生性疾病:病例报告及苏格兰成人肾移植人群EB病毒易感性回顾

阅读:2

Abstract

We report a case of high-grade non-Hodgkin's lymphoma following Epstein-Barr virus (EBV) infection in a 38-year-old renal transplant recipient who was successfully treated with rituximab and remains alive 6 years later with reasonable graft function. We subsequently undertook a survey showing that 1.8% of the Scottish adult transplant pool are susceptible to EBV infection. Though a vaccine for EBV is currently not yet available, routine screening of potential renal transplant recipients for EBV should help identify those at increased risk of post-transplant lymhoproliferative disorder (PTLD), while tailoring of immunosuppression and antiviral prophylaxis with Ganciclovir may help reduce the emergence of this potentially life-threatening disease.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。