Functional recognition imaging using artificial neural networks: applications to rapid cellular identification via broadband electromechanical response

使用人工神经网络进行功能识别成像:通过宽带机电响应实现快速细胞识别的应用

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作者:M P Nikiforov, V V Reukov, G L Thompson, A A Vertegel, S Guo, S V Kalinin, S Jesse

Abstract

Functional recognition imaging in scanning probe microscopy (SPM) using artificial neural network identification is demonstrated. This approach utilizes statistical analysis of complex SPM responses at a single spatial location to identify the target behavior, which is reminiscent of associative thinking in the human brain, obviating the need for analytical models. We demonstrate, as an example of recognition imaging, rapid identification of cellular organisms using the difference in electromechanical activity over a broad frequency range. Single-pixel identification of model Micrococcus lysodeikticus and Pseudomonas fluorescens bacteria is achieved, demonstrating the viability of the method.

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