Elicitation of the generalized Shwartzman reaction in rabbits with parenteral iron preparations and bacterial endotoxin

用肠外铁剂和细菌内毒素诱发兔全身性施瓦茨曼反应

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Abstract

Some parenteral iron preparations were examined regarding their ability to act as preparing agents in the elicitation of the generalized Shwartzman reaction in the rabbit. As expression of the generalized Shwartzman reaction bilateral cortical necrosis of the kidneys was demonstrated when Imferon, Iroject, Macofer, and A 2152 were used as preparing agents. No renal lesion was observed when Jectofer was used.

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