Abstract
Forming a significant part of biomass on earth, microorganisms are renowned for their abundance and diversity. From submicroscopic infectious particles (viruses), small unicellular cells (bacteria and yeasts) to multinucleate and multicellular organisms (filamentous fungi, protozoa, and helminths), microorganisms have found their way into virtually every environmental niche, and show little restrain in making their presence felt. While a majority of microorganisms are free-living and involved in the degradation of plant debris and other organic materials, others lead a symbiotic, mutually beneficial life within their hosts. In addition, some microorganisms have the capacity to take advantage of temporary weaknesses in animal and human hosts, causing notable morbidity and mortality. Because clinical manifestations in animals and humans resulting from infections with various microorganisms are often nonspecific (e.g., general malaise and fever), it is necessary to apply laboratory diagnostic means to identify the culprit organisms for treatment and prevention purposes.