Abstract
γδ T cells, a heterogeneous lymphocyte subset operating at the interface between innate and adaptive immunity, mediate ambivalent and context-dependent effects in oncological settings. Recent work by Rozalén et al, (2025) demonstrates that IL-17-secreting γδ T cells favor the outgrowth of TIM-3(+) triple-negative breast cancer metastases by establishing local immunosuppression.