Three new pyrrole alkaloids from the endophytic fungus Albifimbria viridis

从内生真菌 Albifimbria viridis 中分离得到三种新的吡咯生物碱

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Abstract

Three new pyrrole alkaloids albifipyrrols A-C (1-3), were isolated from the endophytic fungus Albifimbria viridis collected from the Chinese medicinal plant. Their structures were elucidated by extensive NMR and HRESIMS spectrometric analyses. All compounds were evaluated for immunosuppressive activity. Fortunately, compound 2 exhibits certain inhibition specifically against the LPS-induced proliferation of B lymphocyte cells with IC(50) value 16.16 μM.

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