Solid-state characterization of triamcinolone acetonide nanosuspensiones by X-ray spectroscopy, ATR Fourier transforms infrared spectroscopy and differential scanning calorimetry analysis

通过 X 射线光谱、ATR 傅立叶变换红外光谱和差示扫描量热法分析对曲安奈德纳米混悬剂进行固态表征

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作者:Eva García-Millán, Mónica Quintáns-Carballo, Francisco Javier Otero-Espinar

Abstract

The data presented in this article describe the physical state of the triamcinolone acetonide (TA) in nanosuspension stabilized with polyvinyl alcohol (PVA) and poloxamer 407 (PL). The data were assessed by X-ray spectroscopy, ATR Fourier transforms infrared spectroscopy measurements (FTIR), and Differential scanning calorimetry (DSC) analysis. PVA, PL and polymeric mixture (PVA and PL) were compared with nanosuspension and the interactions between drug triamcinolone acetonide and polymers were studied. The data are related and are complementary to the research article entitle "Improved release of triamcinolone acetonide from medicated soft contact lenses loaded with drug nanosuspensions" (García-Millán et al., 2017) [1].

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