Environmental Effect of High-voltage Towers on the Cerebellum and Cognitive Impairments in the Monkey

高压塔对猴子小脑和认知障碍的环境影响

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作者:Hamed Aliyari, Hedayat Sahraei, Mohammad Bagher Menhaj, Masoomeh Kazemi, Behrooz Vahidi, Seyed Hossein Hosseinian

Conclusion

The tested monkey's cognitive, biological, and MRI results showed a decrease in visual learning and memory indices.

Methods

Two monkeys have been used, one as a control and the second as a test. The monkey under test was subjected to a simulated HV electrical field of 3 kV/m, 4 hours a day, for 1 month. Behavioral tests were performed using a device designed and built for this purpose. Concentration analysis of adrenocorticotropic hormones (ACTH) and inspection of glucocorticoid receptor gene's (GR) expression were performed by the reverse transcription polymerase chain reaction method. Changes in cerebellar anatomy were examined with magnetic resonance imaging (MRI). All tests were performed before and after the study period and compared with the control monkey.

Results

Cognitive tests showed a significant reduction for the monkey exposed to the HV electrical field in the first week after imposition compared with the same time before. Also, the expression of the GR gene decreased, and the concentration of ACTH hormone in plasma increased. Surveying the level of cerebral MRI images did not show any difference, but hemorrhage was evident in a part of the cerebellum.

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