Profile analysis of emerging respiratory virus in children

儿童新发呼吸道病毒概况分析

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作者:André Luís Elias Moreira, Paulo Alex Neves da Silva, Leandro do Prado Assunção, Mônica de Oliveira Santos, Célia Regina Malveste Ito, Kelliane Martins de Araújo, Marcos de Oliveira Cunha, Vívian da Cunha Rabelo, Paula Pires de Souza, Sibely Braga Santos Maia, Fernanda Aparecida de Oliveira Peixoto, 

Abstract

Acute respiratory infections (ARIs) are caused by a variety of microorganisms. Of all ARIs, 80% are caused by viruses such as human respiratory syncytial virus, metapneumovirus, influenza, parainfluenza, rhinovirus, and, more recently, Sars-CoV-2, which has been responsible for the COVID-19 pandemic. The objective of our study was to evaluate clinical data from a viral panel performed in children hospitalized with SARS or COVID-19 in the infirmary or ICU of 5 pediatric hospitals in the city of Goiânia, Goiás, Brazil. Demographic, clinical, and laboratory data were collected for analysis, and data on the outcomes underwent statistical treatment. A total of 128 patients were selected for the study, 54% of whom were male and 46% female. The viral panel included rhinovirus, COVID-19, metapneumovirus, adenovirus, and parainfluenza. Descriptive analyses of age profile showed differences in the involvement of particular viruses. The percentage of patients who required hospitalization in the ICU, infirmary, as well as individuals who were discharged after therapy or who died, were described. Our work shows that epidemiological surveillance measures are indispensable, especially if used in the continued analysis of viral panels in all pediatric patients with SARS.

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