Abstract
This case series examines mechanical thrombectomy (MT) with thromboaspiration in two infants under 1 year, a rarely performed procedure due to ethical challenges and limited data. Both cases involved thromboembolic complications during intra-arterial chemotherapy for retinoblastoma. An 11-month-old with left posterior inferior cerebellar artery occlusion and a 5-month-old with basilar artery occlusion underwent MT, achieving full recanalization (eTICI = 3) without infarction or hemorrhage. Postoperative imaging confirmed no complications, and both patients had normal neurological outcomes (pedNIHSS = 0). These cases highlight the feasibility and safety of MT in infants, demonstrating its potential to achieve excellent outcomes in high-risk situations. Further research is needed to establish standardized guidelines and expand MT's use in pediatric stroke management.