Potential of microbial-derived biosurfactants for oral applications-a systematic review

微生物衍生的生物表面活性剂在口腔应用的潜力——系统综述

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作者:Z Khairunnisa, N Tuygunov, A Cahyanto, W H Aznita, I A Purwasena, N S M Noor, N H Azami, M N Zakaria

Background

Biosurfactants are amphiphilic compounds produced by various microorganisms. Current research evaluates diverse types of biosurfactants against a range of oral pathogens. Objectives: This systematic review aims to explore the potential of microbial-derived biosurfactants for oral applications. Methodology: A systematic literature search was performed utilizing PubMed-MEDLINE, Scopus, and Web of Science databases with designated keywords. The

Conclusion

Biosurfactants have garnered considerable interest and demonstrated their potential for application in oral health. This is attributed to their surface-active properties, antiadhesive activity, biodegradability, and antimicrobial effectiveness against a variety of oral microorganisms, including bacteria and fungi.

Results

Among the initial 357 findings, ten studies were selected for further analysis. The outcomes of this systematic review reveal that both crude and purified forms of biosurfactants exhibit antimicrobial and antibiofilm properties against various oral pathogens. Noteworthy applications of biosurfactants in oral products include mouthwash, toothpaste, and implant coating.

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