Peptide-nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms?

肽-纳米粒子结合物:下一代诊断和治疗平台?

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作者:Woo-Jin Jeong, Jiyoon Bu, Luke J Kubiatowicz, Stephanie S Chen, YoungSoo Kim, Seungpyo Hong

Abstract

Peptide-nanoparticle conjugates (PNCs) have recently emerged as a versatile tool for biomedical applications. Synergism between the two promising classes of materials allows enhanced control over their biological behaviors, overcoming intrinsic limitations of the individual materials. Over the past decades, a myriad of PNCs has been developed for various applications, such as drug delivery, inhibition of pathogenic biomolecular interactions, molecular imaging, and liquid biopsy. This paper provides a comprehensive overview of existing technologies that have been recently developed in the broad field of PNCs, offering a guideline especially for investigators who are new to this field.

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