Congenital arthrogryposis-hydranencephaly syndrome caused by Akabane virus in newborn calves of Basrah Governorate, Iraq

伊拉克巴士拉省新生小牛患上由阿卡巴内病毒引起的先天性关节挛缩-脑积水综合征

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Abstract

AIM: The study was conducted in Basrah, Iraq, to diagnose congenital arthrogryposis-hydranencephaly syndrome caused by Akabane virus (AKAV) in calves. MATERIALS AND METHODS: Affected animals (42 calves) are about 2-27 days old from both sexes show signs of arthrogryposis and hydranencephaly. Eight clinically healthy newborn calves were considered as controls. Diagnosis of AKAV was confirmed using a competition enzyme-linked immunosorbent assay test. RESULTS: Results show that all affected calves were found seropositive. Furthermore, a significant increase in total leukocyte count in diseased calves due to a significant increase in the absolute lymphocyte number indicated in affected calves than in controls. Moreover, a significant increase in sedimentation rate of erythrocytes was also encountered in diseased calves than in controls. In addition, a significant increase in haptoglobin level and fibrinogen was also detected. CONCLUSION: Diagnosis of AKAV infection of Basrah Governorate, Iraq, will provide useful epidemiological information for cattle and other domesticated animals. Therefore, abortion could be prevented and controlled.

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