Resistance Training Combined With Cognitive Training Increases Brain Derived Neurotrophic Factor and Improves Cognitive Function in Healthy Older Adults

阻力训练与认知训练相结合可增加脑源性神经营养因子并改善健康老年人的认知功能

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作者:Luz Albany Arcila Castaño, Vivian Castillo de Lima, João Francisco Barbieri, Erick Guilherme Peixoto de Lucena, Arthur Fernandes Gáspari, Hidenori Arai, Camila Vieira Ligo Teixeira, Hélio José Coelho-Júnior, Marco Carlos Uchida

Background

The present study compared the effects of a traditional resistance training (TRT) and resistance training combined with cognitive task (RT + CT) on body composition, physical performance, cognitive function, and plasma brain-derived neurotrophic factor (BNDF) levels in older adults.

Conclusion

The RT program associated with a cognitive task, improved physical and cognitive performance in healthy older adults.

Methods

Thirty community-dwelling older adults were randomized into TRT (70.0 ± 8.1; 25% men) and RT + CT (66.3 ± 4.6; 31% men). Exercise groups performed a similar resistance training (RT) program, twice a week over 16 weeks. Cognitive Training involved performing verbal fluency simultaneously with RT. Exercise sessions (eight resistance exercises) were performed 2-3 sets, 8-15 repetitions at 60%-70% of 1-repetition maximum (1RM). Body composition, physical function, cognitive performance, and BDNF levels were assessed before and after intervention period.

Results

The physical performance was similarly improved in response to both TRT and RT + CT (p = 0.001). However, exclusive improvements on cognitive function (p < 0.001) and BDNF levels (p = 0.001) were observed only after RT + CT.

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