Abstract
OBJECTIVES: To present the findings, conclusions, and recommendations of the National Academies report Reproducibility and Replicability in Science, as relevant to the nutrition research community, and to engage in a discussion of implications for nutrition research. METHODS: The report was developed by a committee of individuals with expertise in research methodologies across a range to disciplines and fields, including nutrition research. The committee was charged with assessing what is known about the extent of the issues of replication and reproducibility (R&R) in scientific and engineering research. To inform the development of the report, the committee held several evidence-gathering sessions and reviewed published literature. RESULTS: Reproducibility and Replicability in Science will be published in spring 2019, after undergoing the National Academies’ rigorous review process. The report will include (1) definitions of “reproducibility” and “replication,” (2) an assessment of what is known about the extent of R&R in scientific and engineering research, (3) consideration of whether a lack of R&R impacts the health or the public's perception of research, (4) a review of approaches to improve R&R, (5) examination of factors affecting R&R, (6) consideration of R&R across a range of research methodologies, and (7) conclusions and recommendations for improving R&R and highlighting examples of good practices. CONCLUSIONS: Conclusions remain confidential until the report has cleared the National Academies report review process. The report will include conclusions and recommendations for improving R&R, with relevance for nutrition research. FUNDING SOURCES: This study was supported by the U.S. National Science Foundation and the Alfred P. Sloan Foundation.