Abstract
As the first phase of one of the most ambitious projects in the history of neuroscience comes to a close, one early and influential leader and his younger colleague explain its evolution and underpinnings. Its goal “is to build a ‘network map’ that will shed light on the anatomical and functional connectivity within the healthy human brain, as well as to produce a body of data that will facilitate research into brain disorders such as dyslexia, autism, Alzheimer’s disease, and schizophrenia.”