Abstract
Solvent evaporation, a ubiquitous yet often limiting step in chemical synthesis, routinely creates critical bottlenecks in research workflows. We introduce a novel benchtop solvent evaporation platform engineered to dramatically accelerate this process within a standard fume hood. Designed with flexible hardware and software architecture, this system is primed for autonomous control via Python scripting, transitioning from its current manual operation to fully automated capabilities. The platform offers two versatile configurations: a single-container evaporator for individual sample precision and a batch evaporator for high-throughput, simultaneous processing of multiple vials. Both variants feature a custom-designed, chemically inert 3D-printed adapter, equipped with precise compressed nitrogen and air inlet ports, alongside an efficient exhaust. Rapid and uniform solvent removal is achieved through a synergistic approach: integrated heating pads maintain optimal temperature in the vial block, while pressurized nitrogen is directed through uniquely helical channels within the adapter, generating a powerful vortex that significantly accelerates evaporation. Rigorous studies confirm the platform's robust and uniform solvent removal performance, conclusively demonstrating its potential to fundamentally alleviate key bottlenecks in chemical synthesis, thereby enhancing productivity and accelerating discovery. This innovative system represents a vital step towards fully automated and efficient chemical laboratories.