The Anticancer Role of Cerium Oxide Nanoparticles by Inducing Antioxidant Activity in Esophageal Cancer and Cancer Stem-Like ESCC Spheres
二氧化铈纳米粒子通过诱导食管癌和癌干样 ESCC 球体中的抗氧化活性发挥抗癌作用
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作者：Hossein Javid, Seyed Isaac Hashemy, Mohammad Foad Heidari, Ali Esparham, Sattar Gorgani-Firuzjaee
Conclusion
These results suggest the potential anticancer effect of CNP by elevating antioxidant levels and expressions, and reducing oxidant levels.
Results
CSC-LC had significantly elevated SOX4 and OCT4 pluripotent genes. The ROS and MDA levels were significantly reduced in both YM1 and CSC-LC spheres after treatment with CNP. Also, the antioxidant levels and expressions were elevated significantly in both cell lines after CNP treatment.
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