Patch test results in children and adolescents. Study from the Santa Casa de Belo Horizonte Dermatology Clinic, Brazil, from 2003 to 2010

儿童和青少年的斑贴试验结果。巴西 Santa Casa de Belo Horizonte 皮肤病诊所 2003 年至 2010 年的研究

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作者:Dulcilea Ferraz Rodrigues, Eugênio Marcos Andrade Goulart

Background

Patch testing is an efficient method to identify the allergen responsible for allergic contact dermatitis.

Conclusion

Nickel and fragrances were the only positive (and relevant) allergens in children. Nickel and tosylamide formaldehyde resin were the most frequent and relevant allergens among adolescents.

Methods

Cross-sectional study to assess patch test

Objective

To evaluate the

Results

Seventy four (59.2%) patients had "at least one positive reaction" to the patch test. Among these positive tests, 77.0% were deemed relevant. The most frequent allergens were nickel (36.8%), thimerosal (18.4%), tosylamide formaldehyde resin (6.8%), neomycin (6.4%), cobalt (4.0%) and fragrance mix I (4.0%). The most frequent positive tests came from adolescents (p=0.0014) and females (p=0.0002). There was no relevant statistical difference concerning contact sensitizations among patients with or without atopic history. However, there were significant differences regarding sensitization to nickel (p=0.029) and thimerosal (p=0.042) between the two age groups under study, while adolescents were the most affected.

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