Abstract
BACKGROUND: Mandibular reconstruction is a critical procedure in the management of defects caused by trauma, tumors, or congenital anomalies. Traditional methods often face challenges such as poor fit, extended surgery time, and postoperative complications. The advent of 3D printing technology allows for the precise fabrication of titanium implants tailored to individual anatomy. This study evaluates the clinical outcomes of using 3D-printed titanium implants in mandibular reconstruction. MATERIALS AND METHODS: This prospective study involved 30 patients (mean age: 45 ± 12 years) with mandibular defects requiring reconstruction. Customized 3D-printed titanium implants were designed using preoperative CT scans and fabricated using laser powder bed fusion technology. Surgical procedures included implant placement combined with soft tissue grafts where necessary. Follow-ups were conducted at 1, 3, 6, and 12 months postoperatively to assess implant stability, functional outcomes (mastication and speech), and aesthetic satisfaction. Data were analyzed using descriptive statistics and paired t-tests for functional improvement. RESULTS: All patients successfully underwent implantation without intraoperative complications. At 12 months, the implant survival rate was 96.7%. Functional assessment showed a significant improvement in chewing efficiency (mean increase: 40%, P < 0.001) and speech clarity (mean increase: 30%, P < 0.001). Patient satisfaction regarding aesthetics was high, with 85% rating outcomes as excellent. Postoperative complications included mild infection in two patients (6.7%) and implant loosening in one patient (3.3%), all managed successfully. CONCLUSION: 3D-printed titanium implants demonstrated excellent clinical efficacy and safety in mandibular reconstruction, offering significant functional and aesthetic benefits. The technology holds promise for personalized care in maxillofacial surgery, though long-term studies are needed to confirm these findings.